The latest squad news from Colney
"It will be a last minute decision with Andre as he's not fully fit," Neil explained on Wednesday.
"Matt's not got a timeline in terms of his recovery. He's doing well at the minute, he's ticking most boxes, but he's a high-impact, high-energy player so he's got to be 100% right."
City's trip to Tottenham marks the first of three Barclays Premier League matches in the space of seven days, and Neil stressed the need to keep his squad fresh during a hectic festive schedule.
"With the intensity the games are played at, to ask the same eleven players to churn it out at that level is extremely difficult," he added.