Daniel Farke delivered an injury blow at his pre-Reading press conference on Tuesday, announcing that in-form winger Onel Hernandez is set to miss the next 2 and a half weeks with a hernia problem.
Hernandez was named the Falcon Cranes Player of the Month for August prior to the game with Middlesbrough, following his two goals, three assists and impressive performances from the left flank.
However, the City Head Coach said that his injury requires surgery.
Farke said: "Sadly, we will have to do without Onel Hernandez. He has a hernia problem and he will be operated on tomorrow. He will be out for, I would say maybe back for the home game with Stoke [October 6], but definitely for the next 2 and a half weeks.
"He's had the problem for several weeks. We were hoping to able to stretch it until the summer break because it's not like a broken leg. It's pretty often that you can do this during a break but it depends how much pain the player has.
"We were a bit concerned at the end of last week. He handled it during the game against Middlesbrough, but after the the game, he said to us: 'It's really uncomfortable.'
"Of course, we are all a bit sad and disappointed because he's been crucial for us. But [the surgery] is the best for him."
Grant Hanley, Louis Thompson and Kenny McLean will continue their recoveries from respective injuries and therefore miss the visit to the Madejski Stadium. Ivo Pinto will also miss out but Farke said his return isn't too far away.
"It's good news with him," the Boss added. "He returned back to team training today [Tuesday] but it's too early for Reading. He's only had one session with the team.
"He won't travel with us [to Reading] but it's good to have him back and he could be available for the next game against QPR."
Farke also delivered negative news on Ben Marshall: "We will have to do without him. He had a bad stomach overnight and wasn't able to sleep so he's not able to travel with us."
Marco Stiepermann was withdrawn with a slight knock on Saturday and Farke said a late decision will be made on his fitness.
"He got a hit against his hip flexor. We were really concerned after the game and there is still a small question mark behind his name today.
"He's had some tablets and was able to train so we will see how he reacts in the afternoon and overnight so I hope he's available because he was crucial to our win on Saturday."