Grant Hanley returned for Scotland on Sunday evening to boost his chances of competing at a first major tournament.
The Norwich City captain was forced to miss their previous EURO 2020 warm-up fixture against the Netherlands on Thursday after teammate John Fleck contracted COVID-19, meaning a select group of Scotsmen had to self-isolate including Hanley.
However, Hanley returned to play the full 90 minutes against Luxembourg as Steve Clarke's men won 1-0 thanks to Che Adams' first-half effort.
Scotland get their EURO 2020 campaign underway on Monday week against Czech Republic (3pm UK).
On the opposing side for Luxembourg was Danel Sinani, who played 71 minutes of the encounter.
Elsewhere, Tim Krul and Dimitris Giannoulis were unused substitutes for Netherlands and Greece respectively as they both picked up victories.
Giannoulis's Greece failed to qualify for EURO 2020, whereas Krul and the Netherlands get their campaign underway on Sunday (9pm UK) against Ukraine.